منابع مشابه
Net intestinal transport of oxalate reflects passive absorption and SLC26A6-mediated secretion.
Mice lacking the oxalate transporter SLC26A6 develop hyperoxalemia, hyperoxaluria, and calcium-oxalate stones as a result of a defect in intestinal oxalate secretion, but what accounts for the absorptive oxalate flux remains unknown. We measured transepithelial absorption of [(14)C]oxalate simultaneously with the flux of [(3)H]mannitol, a marker of the paracellular pathway, across intestine fro...
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Desferroxamine (Desferal) is used tochelate iron in thalassemia, a disease of very high prevalence in various parts of lran. We have investigated intestinal zinc absorption in Desferal-treated rats which, in pilot experiments, showed low serum levels of both iron and zinc. Intraperitoneal administration of ten 0.5 g doses of Desferal (one injection every other day) to male rats produced sev...
متن کاملIntestinal Folate Absorption
and 2%, respectively, was converted to 5-AMeFH4. In contrast, less than 4% of the folate transferred across ileal mucosa was 5-MeFH4 when the initial mucosa concentration was 20 nM. Specific activity of dihydrofolate (DHF) reductase, the enzyme responsible for converting PGA to tetrahydrofolic acid, was measured in villus homogenates and was significantly greater in the jejunum than in the ileu...
متن کاملIntestinal Absorption of Fats.
Great progress in understanding the mechanisms of fat absorption by the mammalian intestine has been made in the past decade and a half. In contrast to the contentions of rival theorists of the century before this, it has been possible for many laboratories throughout the world to confirm observations made by use of the new tools available, and to come to agreement on current interpretations of...
متن کاملIntestinal lipid absorption.
Our knowledge of the uptake and transport of dietary fat and fat-soluble vitamins has advanced considerably. Researchers have identified several new mechanisms by which lipids are taken up by enterocytes and packaged as chylomicrons for export into the lymphatic system or clarified the actions of mechanisms previously known to participate in these processes. Fatty acids are taken up by enterocy...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 1974
ISSN: 0016-5085
DOI: 10.1016/s0016-5085(19)32846-x